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Oncotarget News

New Radiofrequency Therapy Slows Glioblastoma Growth and Targets Tumor Stem Cells

October 14, 2025

Intrabuccal administration of amplitude-modulated 27.12 MHz radiofrequency electromagnetic fields (AM RF EMF) resulting in the systemic delivery of low and safe levels of AM RF EMF has shown activity... read more

Oncotarget

Engineered Bacterial Therapy Activates Immune Response in Cancer Preclinical Studies

October 8, 2025

ACTM-838 showed durable anti-tumor efficacy in multiple murine tumor models and synergized with anti-PD1 therapy in combination.”BUFFALO, NY - October 8, 2025 – A new research paper was published in Volume... read more

Oncotarget

Oncotarget Editor-in-Chief Wafik S. El-Deiry Chairs 2025 WIN Symposium in Collaboration with APM in Philadelphia

October 1, 2025

The WIN Symposium featured as the Oncology Track at the APM Annual Conference 2025 unites global leaders in oncology, translational science, and precision medicine.BUFFALO, NY - October 1, 2025&... read more

Oncotarget

Loss of Trp53 Gene Promotes Tumor Growth and Immune Suppression in Ovarian Cancer

September 24, 2025

These results highlight potential mechanisms by which loss of p53 function contributes to an immunosuppressive microenvironment in HGSC, and provide insight into the role of ovarian and peritoneal microenvironments in... read more

Oncotarget

Blocking Protein Control Pathway Slows Rhabdomyosarcoma Growth in Mice

August 29, 2025

Together, these findings confirm that proteostasis inhibition can slow RMS growth and suggest that targeting compensatory network components might yield synergistic outcomes.”BUFFALO, NY - August 29, 2025 – A new research... read more

Oncotarget

Behind the Study: R-spondin Family Roles in Metastatic Prostate Cancer

August 26, 2025

Aiden Deacon from the University of Minnesota-Twin Cities, Minneapolis, discusses a research paper he co-authored that was published in Volume 16 of Oncotarget, titled “Dissecting the functional differences and clinical... read more

Oncotarget

Aramchol Boosts Regorafenib Effectiveness in Gastrointestinal Tumors

August 19, 2025

We determined in GI tumor cells that regorafenib interacted with aramchol to promote tumor cell killing.”BUFFALO, NY - August 19, 2025 – A new research paper was published in Volume 16... read more