Press Releases | Page 20 of 42

Behind the Study: Osteopontin Induces Mitochondrial Biogenesis in Deadherent Cancer Cells

December 14, 2023

Dr. Georg F. Weber, from the University of Cincinnati Academic Health Center, James L. Winkle College of Pharmacy, details a research paper he co-authored that was published by Oncotarget in… read more

Oncotarget

Cytostatic Persister Cancer Cells: Therapeutic Opportunities and Challenges

December 13, 2023

“[...] we anticipate that heterogeneous persister populations are inevitable in [cancer] treatment.” BUFFALO, NY- December 13, 2023 – A new editorial paper was published in Oncotarget's Volume 14 on December… read more

Oncotarget

Risk Factors for Long-Term Arm Morbidities Following Breast Cancer Treatments: A Systematic Review

December 11, 2023

“This review revealed 29 primary risk factors associated with arm morbidity after breast cancer treatment.” BUFFALO, NY- December 11, 2023 – A new review paper was published in Oncotarget's Volume… read more

Figure 3: Patient examples of inverse correlation of BCMA and FLC changes during course of therapy.

Oncotarget

BCMA+ EV Levels Correlate With Myeloma Response to Belantamab-Mafodotin

December 6, 2023

“Measurement of BCMA-EV can thus help in identifying resistance mechanisms and side effects of BCMA targeted therapies in future studies.” BUFFALO, NY- December 6, 2023 – A new research paper… read more

Figure 5: The mediators of mitochondrial biogenesis are required for cancer spread. "Osteopontin induces mitochondrial biogenesis in deadherent cancer cells"

Oncotarget

Osteopontin Induces Mitochondrial Biogenesis in Deadherent Cancer Cells

December 4, 2023

“Here, we study the induction of mitochondrial biogenesis by Osteopontin variants in deadherent breast tumor cells.” BUFFALO, NY- December 4, 2023 – A new research paper was published in Oncotarget's… read more

Oncotarget

The Double-Edge Sword of CRISPR Application for In Vivo Studies

November 28, 2023

“The Achilles’ heel of CRISPR application is the delivery of sgRNA/Cas9 to the desired tissues.” BUFFALO, NY- November 28, 2023 – A new editorial paper was published in Oncotarget's Volume… read more

Oncotarget

Targeting Ras With Protein Engineering

November 27, 2023

“While Ras’s relationship to cancer has been long established [37], it has been considered an undruggable target for many years.” BUFFALO, NY- November 27, 2023 – A recent review paper… read more

Figure 2: The spectrum of pathogenic variants in the early-onset breast cancer cohort.

Oncotarget

Genetic Predisposition to Early Breast Cancer in Kazakh Women

November 22, 2023

“Our study may reveal previously uncharacterized population-specific variants that may increase the risk of BC in the Kazakh population.” BUFFALO, NY- November 22, 2023 – A new research paper was… read more

Figure 1: Chromatin landscape of the glioma GWAS locus rs55705857 in the melanocyte lineage.

Oncotarget

Predicting the Molecular Functions of Regulatory Genetic Variants Associated With Cancer

November 20, 2023

“Effectively integrating these rich resources with GWAS results will continue to help prioritize causative inherited genetic variants and improve our molecular understanding of disease etiology [...]” BUFFALO, NY- November 20,… read more

Oncotarget

Obesity Paradox and Lung Cancer, Metformin-based Therapeutic Opportunity?

November 15, 2023

“These findings suggest a strong sensitization by the addition of metformin in obese population, suggesting that biochemical and molecular differences influence the treatment response.” BUFFALO, NY- November 15, 2023 –… read more