Tag: Antibodies

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Oncotarget

New Antibody Selectively Targets Immune Cells That Suppress Anti-Tumor Responses

July 16, 2025

Taken together, our studies suggest that 2B010 represents an anti-CD25 mAb with unique properties in that it deleted Treg from an inflammatory environment (GVHD) as well as from the TME.”... read more

Oncotarget

Breakthroughs in Cell-Penetrating Monoclonal Antibody Therapies

December 11, 2024

Monoclonal antibodies (mAb) have emerged as a promising tool in advancing personalized medicine.”BUFFALO, NY - December 11, 2024 – A news feature on the research paper “Next-generation cell-penetrating antibodies for tumor... read more

Figure 2: A comparative analysis of G4 landscape in cultured cells using AbC G4-ChIP. antibody

Oncotarget

A New Antibody Capture Method Reveals G-quadruplex Landscape and its Regulation

March 18, 2024

we present an improved method for G4 landscape determination and by applying it we show that sequence property-specific constraints of the nuclear environment mitigate G4 formation.”BUFFALO, NY- March 18,... read more

Oncotarget

Oncotarget | Therapeutic Efficacy of Humanized JAA-F11 Anti-Thomsen-Friedenreich Antibody Constructs H2aL2a and H3L3 in Human Breast and Lung Cancer Xenograft Models

October 25, 2022

The potential therapeutic efficacy of the humanized antibodies to TF-Ag-α, hJAA-F11-H2aL2a and hJAA-F11-H3L3, was assessed in human breast and lung cancer xenograft models.”BUFFALO, NY- October 25, 2022 – A new... read more

Oncotarget

Behind the Study: Oral Squamous Carcinoma Cell Migration and Viability

August 30, 2021

Behind the Study is a series of transcribed videos from researchers elaborating on their oncology-focused studies published by Oncotarget. A new Behind the Study is released each Monday.... read more

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