Oncotarget.net features press releases on the latest oncology research, as well as interviews from the distinguished network of authors who continue to publish their research with Oncotarget.

Tag: BRAF

Oncotarget

Protein GSK3β Offers New Angle on Overcoming Melanoma Drug Resistance

April 11, 2025

“Inhibitors of GSK3β reduce the cell viability of BRAFi-resistant melanoma cell lines and thus may holds promise as a novel strategy to overcome BRAFi resistance and melanoma progression.” BUFFALO, NY… read more

Oncotarget

Response of BRAF-Mutated Spindle Cell Sarcoma to BRAF/MEK Inhibitors

August 14, 2024

“This is the first report of spindle cell sarcoma BRAF V600E/S607T double-mutated, responding to a combination of B-Raf and MEK inhibitors.” BUFFALO, NY- August 14, 2024 – A new case… read more

Targeting the multifaceted BRAF in cancer: New directions

Oncotarget

New Directions in Targeting the Multifaceted BRAF in Cancer

August 12, 2024

“Here we discuss the diverse forms of BRAF alterations found in human cancers and the strategies to inhibit them in patients harboring cancers of distinct origins.” BUFFALO, NY- August 12,… read more

Figure 1: Representative histopathologic slides stained with hematoxylin and eosin of thyroid cancer from well-differentiated to dedifferentiated states.

Oncotarget

Genetic Alterations in Thyroid Cancer Mediate Resistance to BRAF Inhibition and Anaplastic Transformation

January 29, 2024

“An improved understanding of the molecular basis of thyroid cancer has led to the development of new targeted agents.” BUFFALO, NY- January 29, 2024 – A new research perspective was… read more