![Figure 1: Mechanism of action of MTAP along with downstream effects from its loss.](https://www.oncotarget.net/wp-content/uploads/2023/03/Screen-Shot-2023-03-14-at-12.54.31-PM-300x180.png)
Oncotarget | MTAP Loss in Metastatic Breast Cancer Patients: Genomic Landscape
March 14, 2023
In breast cancer, MTAP downregulation activates ornithine decarboxylase (ODC) which in turn leads to formation of putrescine which promotes tumor migration, invasion and angiogenesis [15].” BUFFALO, NY- March 14,... read more