Tag: Press Release

Immunotherapy Success in KRAS G12C Adenosquamous Pancreatic Cancer

November 4, 2024

“Here, we present a case of metastatic ASCP with a KRAS G12C mutation refractory to multiple lines of systemic therapy, including platinum-based chemotherapy and targeted inhibition of KRAS G12C.” BUFFALO,… read more

Oncotarget

Tumor Dormancy Initiated by Lymphovascular Embolus

October 30, 2024

“Both our experimental as well as observational studies indicate that in vivo lymphovascular tumor emboli and their in vitro spheroid equivalent initiate dormancy through these pathways.” BUFFALO, NY- October 30,… read more

Oncotarget

Complete Response to Encorafenib + Binimetinib in BRAF V600E-Mutant Tumor

October 29, 2024

“This case report highlights the importance of full tumor genotyping to identify potentially actionable targets in rare tumors such as malignant glomus tumors.” BUFFALO, NY- October 29, 2024 – A… read more

Oncotarget

How Blood Cancer Cells Rewire to Evade Drug Treatment

October 23, 2024

“[...] drugs that target individual signalling pathways in AML often fail to stop proliferation malignant growth, due to the wide variety, redundancy and cross talk between multiple pathways regulating and… read more

Oncotarget

Next-Gen Cell-Penetrating Antibodies for Tumor Targeting and RAD51 Inhibition

October 21, 2024

“Overall, the data presented in this study affirm that humanizing 3E10 preserves its crucial biological properties essential for therapeutic efficacy.” BUFFALO, NY- October 21, 2024 – A new research paper… read more

Oncotarget

Molecular Chaperones: Guardians of Tumor Suppressor Stability

October 16, 2024

“Focusing on the holistic lifecycle of these proteins reveals commonalities between the widely diverse group of tumor suppressors, which is invaluable to inform therapy development for multiple cancers.” BUFFALO, NY-… read more