research paper Archives

Oncotarget News

Blocking Protein Control Pathway Slows Rhabdomyosarcoma Growth in Mice

August 29, 2025

Together, these findings confirm that proteostasis inhibition can slow RMS growth and suggest that targeting compensatory network components might yield synergistic outcomes.”BUFFALO, NY - August 29, 2025 – A new research... read more

Oncotarget

Aramchol Boosts Regorafenib Effectiveness in Gastrointestinal Tumors

August 19, 2025

We determined in GI tumor cells that regorafenib interacted with aramchol to promote tumor cell killing.”BUFFALO, NY - August 19, 2025 – A new research paper was published in Volume 16... read more

Oncotarget

FDA-Approved MI Cancer Seek Test Enhances Tumor Profiling for Precision Oncology

August 15, 2025

Accordingly, MI Cancer Seek represents a safe and effective comprehensive molecular test option supporting biomarker-directed care for oncology patients.”BUFFALO, NY - August 15, 2025 – A new research paper was published... read more

Oncotarget

New Compound Disrupts Survival Pathways in Aromatase Inhibitor-Resistant Breast Cancer Cells

August 13, 2025

The ability of PCAIs to mitigate various cancer hallmarks in the various cancer cell lines has been well established.”BUFFALO, NY - August 13, 2025 – A new research paper was published... read more

Oncotarget

New Gene Linked to Aggressive, Treatment-Resistant Prostate Cancer

August 11, 2025

These findings highlight that, in PC, RSPO2 functions as a unique member of the R-spondin family by promoting genes and signaling pathways associated with aggressive PC, and RSPO2 amplifications are... read more

Oncotarget

Comprehensive Genomic Testing Reveals Treatment Targets in 90% of Advanced Solid Tumors

July 29, 2025

The broad capabilities of the OncoExTra assay detected therapeutically actionable and other clinically relevant genomic events that can inform clinical decision-making for patients with advanced solid tumors.”BUFFALO, NY - July... read more

Oncotarget

Cholesterol-Lowering Drugs Show Promise Against Colorectal Cancer

July 22, 2025

Our findings provide direct evidence that statins selectively modulate key components of the Wnt/β-catenin signaling pathway, a major driver of adenoma formation, including members of the special AT-rich sequence-binding (... read more