Oncotarget | New Oncology-Focused Papers Published in Volume 13

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BUFFALO, NY- June 23, 2022 – At the start of 2022, Oncotarget began publishing research papers in a continuous publishing format in yearly volumes. As of June 23, 2022, Oncotarget has published a total of 64 high-impact, oncology-focused papers within Volume 13. Oncotarget’s Volume 13 consists of papers authored by numerous prestigious researchers and scientists from world-renowned institutions. Select papers in this Volume were chosen for inclusion in Oncotarget’s Special Collections on breast and lung cancer research.

You can click the links below to learn more about the groundbreaking research papers and perspectives, meeting and case reports, commentaries, editorials, and reviews published by Oncotarget in 2022. You may also visit the Oncotarget YouTube channel to watch video previews of papers published by Oncotarget.

  1. Research Paper: Transcriptomics reveals in vivo efficacy of PARP inhibitor combinatorial synergy with platinum-based chemotherapy in human non-small cell lung carcinoma models
    Authors: Lindsay R. Stolzenburg, Barrett Ainsworth, Bridget Riley-Gillis, Tibor Pakozdi, Areej Ammar, Paul A. Ellis, Julie L. Wilsbacher, and Cyril Y. Ramathal
  1. Editorial: Unravelling the underpinnings of hyperprogression and immunotherapy: back to the bench
    Authors: Vivek Subbiah and Razelle Kurzrock
  1. Commentary: Oxygen-independent, CDK4/CDK6-dependent degradation of hypoxia-inducible factor-1α takes cancers’ breath away
    Author: Len Neckers
  1. Research Perspective: The “Immunoscore” in rectal cancer: could we search quality beyond quantity of life?
    Authors: Amos Kirilovsky, Carine El Sissy, Guy Zeitoun, Florence Marliot, Nacilla Haicheur, Christine Lagorce-Pagès, Julien Taieb, Mehdi Karoui, Petra Custers, Edina Dizdarevic, Soledad Iseas, Torben Frøstrup Hansen, Lars Henrik Jensen, Geerard Beets, Jean Pierre Gérard, Mireia Castillo-Martin, Nuno Figueiredo, Angelita Habr-Gama, Rodrigo Perez, Jérôme Galon, and Franck Pagès
  1. Research Paper: Induction of serine hydroxymethyltransferase 2 promotes tumorigenesis and metastasis in neuroblastoma
    Authors: Rachael A. Clark, Jingbo Qiao, Jillian C. Jacobson, and Dai H. Chung
  1. Research Paper: The androgen receptor inhibits transcription of GPER1 by preventing Sp1 and Sp3 from binding to the promoters in prostate cancer cells
    Authors: Austin McDermott, KyoungHyun Kim, Susan Kasper, Shuk-Mei Ho, and Yuet-Kin Leung
  1. Research Paper: Early detection of treatment futility in patients with metastatic colorectal cancer
    Authors: Jodi I. Rattner, Karen A. Kopciuk, Hans J. Vogel, Patricia A. Tang, Jeremy D. Shapiro, Dongsheng Tu, Derek J. Jonker, Lillian L. Siu, Chris J. O’Callaghan, and Oliver F. Bathe
  1. Research Paper: Altered glycosylation of several metastasis-associated glycoproteins with terminal GalNAc defines the highly invasive cancer cell phenotype
    Authors: Elham Khosrowabadi, Tomasz Wenta, Salla Keskitalo, Aki Manninen, and Sakari Kellokumpu
  1. Editorial: Are 50 years enough to prove the brilliant Dilman’s idea?
    Author: Vladimir N. Anisimov
  1.  Research Paper: GZ17-6.02 and palbociclib interact to kill ER+ breast cancer cells
    Authors: Laurence Booth, Cameron West, Robert P. Moore, Daniel Von Hoff, and Paul Dent
  1.  Research Paper: Exploiting protein family and protein network data to identify novel drug targets for bladder cancer
    Authors: Tolulope Tosin Adeyelu, Aurelio A. Moya-Garcia, and Christine Orengo
  1.  Commentary: Redefining and expanding the sphere of influence of BRCA in breast and colorectal cancers and beyond
    Author: Emil Lou
  1.  Research Paper: Suppressive GLI2 fragment enhances liver metastasis in colorectal cancer
    Authors: Ruiko Ogata, Shiori Mori, Hitoshi Ohmori, Shingo Kishi, Rina Fujiwara-Tani, Takamitsu Sasaki, Yukiko Nishiguchi, Chie Nakashima, Kei Goto, Isao Kawahara, Yi Luo, and Hiroki Kuniyasu
  1.  Research Paper: Chimeric chromosome landscapes of human somatic cell cultures show dependence on stress and regulation of genomic repeats by CGGBP1
    Authors: Subhamoy Datta, Manthan Patel, Sukesh Kashyap, Divyesh Patel, and Umashankar Singh
  1.  Research Paper: Synthesis of a novel nanobioconjugate for targeted photodynamic therapy of colon cancer enhanced with cannabidiol
    Authors: Nkune Williams Nkune, Cherie Ann Kruger, and Heidi Abrahamse
  1.  Meeting Report: Seventh BHD international symposium: recent scientific and clinical advancement
    Authors: Mark R. Woodford, Avgi Andreou, Masaya Baba, Irma van de Beek, Chiara Di Malta, Iris Glykofridis, Hannah Grimes, Elizabeth P. Henske, Othon Iliopoulos, Masatoshi Kurihara, Romain Lazor, W. Marston Linehan, Kenki Matsumoto, Stefan J. Marciniak, Yukiko Namba, Arnim Pause, Neil Rajan, Anindita Ray, Laura S. Schmidt, Wei Shi, Ortrud K. Steinlein, Julia Thierauf, Roberto Zoncu, Anna Webb, and Mehdi Mollapour
  1.  Research Paper: Influence of nutrition on stage-stratified survival in gastric cancer patients with postoperative complications
    Authors: Noriyuki Hirahara, Takeshi Matsubara, Shunsuke Kaji, Yuki Uchida, Ryoji Hyakudomi, Tetsu Yamamoto, Kiyoe Takai, Yohei Sasaki, Koki Kawakami, and Yoshitsugu Tajima
  1.  Research Paper: Common cancer treatments targeting DNA double strand breaks affect long-term memory and relate to immediate early gene expression in a sex-dependent manner
    Authors: Sydney Weber Boutros, Destine Krenik, Sarah Holden, Vivek K. Unni, and Jacob Raber
  1.  Research Paper: Plasma biomarkers reflecting high oxidative stress in the prediction of myocardial injury due to anthracycline chemotherapy and the effect of carvedilol: insights from the CECCY Trial
    Authors: Mauro Rogério de Barros Wanderley Jr., Mônica Samuel Ávila, Miguel Morita Fernandes-Silva, Fátima das Dores Cruz, Sara Michelly Gonçalves Brandão, Vagner Oliveira Carvalho Rigaud, Ludhmila Abrahão Hajjar, Roberto Kalil Filho, Edécio Cunha-Neto, Edimar Alcides Bocchi, and Silvia Moreira Ayub-Ferreira 
  2. Research Paper: Impact of the glutathione synthesis pathway on sulfasalazine-treated endometrial cancer
    Authors: Kanako Sendo, Manabu Seino, Tsuyoshi Ohta, and Satoru Nagase
  1.  Research Paper: Exploring the synergistic effects of cabozantinib and a programmed cell death protein 1 inhibitor in metastatic renal cell carcinoma with machine learning
    Authors: Ignacio Durán, Daniel Castellano, Javier Puente, Lidia Martín-Couce, Esther Bello, Urbano Anido, José Manuel Mas, and Luis Costa
  1.  Research Paper: Real-world survival analysis by tumor mutational burden in non-small cell lung cancer: a multisite U.S. study
    Authors: Connor Willis, Hillevi Bauer, Trang H. Au, Jyothi Menon, Sudhir Unni, Dao Tran, Zachary Rivers, Wallace Akerley, Matthew B. Schabath, Firas Badin, Ashley Sekhon, Malini Patel, Bing Xia, Beth Gustafson, John L. Villano, John-Michael Thomas, Solomon J. Lubinga, Michael A. Cantrell, Diana Brixner, and David Stenehjem
  1.  Research Paper: Positive predictive value of ERBB2 copy number gain by tissue or circulating tumor DNA next-generation sequencing across advanced cancers
    Authors: Ami N. Shah, Ashwin Sunderraj, Brian Finkelman, Sharlene H. See, Andrew A. Davis, Lorenzo Gerratana, Firas Wehbe, Neelima Katam, Deva Mahalingam, William J. Gradishar, Amir Behdad, Luis Blanco, and Massimo Cristofanilli
  1.  Research Paper: GZ17-6.02 and axitinib interact to kill renal carcinoma cells
    Authors: Laurence Booth, Cameron West, Robert P. Moore, Daniel Von Hoff, and Paul Dent
  1.  Research Paper: PACER lncRNA regulates COX-2 expression in lung cancer cells
    Authors: Samuel Z. Desind, Joseph R. Iacona, Christina Y. Yu, Antonina Mitrofanova, and Carol S. Lutz
  1.  Research Paper: Antitumor effect of isoquercetin on tissue vasohibin expression and colon cancer vasculature
    Authors: Daniel de Castilho da Silva, Guilherme Di Camillo Orfali, Maycon Giovani Santana, Jessica Kaoru Yamamoto Palma, Isabella Ramos de Oliveira Assunção, Isadora Moraes Marchesi, Ana Yoshie Kitagawa Grizotto, Natália Peres Martinez, Simone Felliti, José Aires Pereira, and Denise Gonçalves Priolli
  1.  Research Paper: ABT199/venetoclax potentiates the cytotoxicity of alkylating agents and fludarabine in acute myeloid leukemia cells
    Authors: Benigno C. Valdez, David Murray, Bin Yuan, Yago Nieto, Uday Popat, and Borje S. Andersson
  1.  Research Paper: Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity
    Authors: Daniel Menendez, Jay R. Anand, Carri C. Murphy, Whitney J. Bell, Jiaqi Fu, Nadia Slepushkina, Eugen Buehler, Scott E. Martin, Madhu Lal-Nag, John L. Nitiss, and Michael A. Resnick
  1.  Research Paper: Telomere shortening accelerates tumor initiation in the L2-IL1B mouse model of Barrett esophagus and emerges as a possible biomarker
    Authors: Vincenz Sahm, Carlo Maurer, Theresa Baumeister, Akanksha Anand, Julia Strangmann, Roland M. Schmid, Timothy C. Wang, and Michael Quante
  1.  Research Paper: A comparison of 64Cu-labeled bi-terminally PEGylated A20FMDV2 peptides targeting integrin ανβ6
    Authors: Truc T. Huynh, Sreeja Sreekumar, Cedric Mpoy, and Buck E. Rogers
  1.  Research Paper: NOTCH1 PEST domain variants are responsive to standard of care treatments despite distinct transformative properties in a breast cancer model
    Authors: Karen Cravero, Morgan V. Pantone, Dong Ho Shin, Riley Bergman, Rory Cochran, David Chu, Daniel J. Zabransky, Swathi Karthikeyan, Ian G. Waters, Natasha Hunter, D. Marc Rosen, Kelly Kyker-Snowman, W. Brian Dalton, Berry Button, Dan Shinn, Hong Yuen Wong, Joshua Donaldson, Paula J. Hurley, Sarah Croessmann, and Ben Ho Park
  1.  Research Paper: Metanephric adenoma: molecular study and review of the literature
    Authors: Enrique Rodríguez-Zarco, Jesús Machuca-Aguado, Laura Macías-García, Ana Vallejo-Benítez, and Juan José Ríos-Martín
  1.  Review: The role of IGF-pathway biomarkers in determining risks, screening, and prognosis in lung cancer
    Authors: Alexander W. Pohlman, Hita Moudgalya, Lia Jordano, Gabriela C. Lobato, David Gerard, Michael J. Liptay, Christopher W. Seder, and Jeffrey A. Borgia
  1.  Review: The long winding road to the safer glucocorticoid receptor (GR) targeting therapies
    Authors: Ekaterina A. Lesovaya, Daria Chudakova, Gleb Baida, Ekaterina M. Zhidkova, Kirill I. Kirsanov, Marianna G. Yakubovskaya, and Irina V. Budunova
  1.  Research Paper: A liquid fraction of extracellular matrix inhibits glioma cell viability in vitro and in vivo
    Authors: Mark H. Murdock, George S. Hussey, Jordan T. Chang, Ryan C. Hill, David G. Nascari, Aparna V. Rao, Kirk C. Hansen, Lesley M. Foley, T. Kevin Hitchens, Nduka M. Amankulor, and Stephen F. Badylak
  1.  Research Paper: Impact of combining vitamin C with radiation therapy in human breast cancer: does it matter?
    Authors: Somayeh Khazaei, Linn Nilsson, Gabriel Adrian, Helga Tryggvadottir, Elise Konradsson, Signe Borgquist, Karolin Isaksson, Crister Ceberg, and Helena Jernström
  1.  Commentary: Defining the mechanisms underlying cyclin dependent kinase control of HIF-1α
    Author: Noel A. Warfel
  1.  Review: Adjuvant osimertinib treatment in patients with early stage NSCLC (IB-IIIA): pathological pathway adaptations
    Authors: Antonio Marchetti, Fiamma Buttitta and Emanuela D’Angelo
  1.  Research Paper: Sequencing of BRCA1/2-alterations using NGS-based technology: annotation as a challenge
    Authors: Silvana Ebner, Ria Winkelmann, Saskia Martin, Jens Köllermann, Peter J. Wild, and Melanie Demes
  1.  Research Paper: An investigation on [5 fluorouracil and epigallocatechin-3-gallate] complex activity on HT-29 cell death and its stability in gastrointestinal fluid
    Authors: Laura Moracci, Francesca Sensi, Andrea Biccari, Sara Crotti, Elisa Gaio, Federico Benetti, Pietro Traldi, Salvatore Pucciarelli, and Marco Agostini
  1.  Research Paper: Transplantation of autologous bone marrow pre-loaded ex vivo with oncolytic myxoma virus is efficacious against drug-resistant Vk*MYC mouse myeloma
    Authors: Nancy Y. Villa, Masmudur M. Rahman, Joseph Mamola, Meaghen E. Sharik, Ana Lemos de Matos, Jacquelyn Kilbourne, Kenneth Lowe, Juliane Daggett-Vondras, Julia D’Isabella, Elizabeth Goras, Marta Chesi, P. Leif Bergsagel, and Grant McFadden
  1.  Research Paper: Cytogenetic and molecular analyses of 291 gastrointestinal stromal tumors: site-specific cytogenetic evolution as evidence of pathogenetic heterogeneity
    Authors: Ludmila Gorunova, Kjetil Boye, Ioannis Panagopoulos, Jeanne-Marie Berner, Bodil Bjerkehagen, Ivar Hompland, Ingvild Lobmaier, Toto Hølmebakk, Tarjei S. Hveem, Sverre Heim, and Francesca Micci
  1.  Research Paper: Correlation of nuclear pIGF-1R/IGF-1R and YAP/TAZ in a tissue microarray with outcomes in osteosarcoma patients
    Authors: Eric R. Molina, Letitia K. Chim, Salah-Eddine Lamhamedi-Cherradi, Sana Mohiuddin, David McCall, Branko Cuglievan, Sandhya Krishnan, Robert W. Porter, Davis R. Ingram, Wei-Lien Wang, Alexander J. Lazar, David W. Scott, Danh D. Truong, Najat C. Daw, Joseph A. Ludwig, and Antonios G. Mikos
  1.  Research Paper: MYH9 binds to dNTPs via deoxyribose moiety and plays an important role in DNA synthesis
    Authors: Pratima Nangia-Makker, Malathy P.V. Shekhar, Victor Hogan, Vitaly Balan, and Avraham Raz
  1.  Review: Patient-derived tumor models are attractive tools to repurpose drugs for ovarian cancer treatment: pre-clinical updates
    Authors: Magdalena Cybula and Magdalena Bieniasz
  1.  Case Report: Resolution of radiation necrosis with bevacizumab following radiation therapy for primary CNS lymphoma
    Authors: Eugene J. Vaios, Kristen A. Batich, Anne F. Buckley, Anastasie Dunn-Pirio, Mallika P. Patel, John P. Kirkpatrick, Ranjit Goudar, and Katherine B. Peters
  1.  Research Paper: Role of the prorenin receptor in endometrial cancer cell growth
    Authors: Jacinta H. Martin, Riazuddin Mohammed, Sarah J. Delforce, David A. Skerrett-Byrne, Celine Corbisier de Meaultsart, Juhura G. Almazi, Andrew N. Stephens, Nicole M. Verrills, Evdokia Dimitriadis, Yu Wang, Eugenie R. Lumbers, and Kirsty G. Pringle
  1.  Research Paper: A novel group of genes that cause endocrine resistance in breast cancer identified by dynamic gene expression analysis
    Authors: Arvand Asghari, Katherine Wall, Michael Gill, Natascha Del Vecchio, Farnaz Allahbakhsh, Jacky Wu, Nan Deng, W. Jim Zheng, Hulin Wu, Michihisa Umetani, and Vahed Maroufy
  1.  Research Paper: Loss of DRO1/CCDC80 in the tumor microenvironment promotes carcinogenesis
    Authors: Jessica I. Christian, Agnieszka Pastula, Andreas Herbst, Jens Neumann, Maximilian K. Marschall, Andrea Ofner, Heike Zierahn, Marlon R. Schneider, Eckhard Wolf, Michael Quante, and Frank T. Kolligs
  1.  Research Paper: Bladder cancer survival in patients with NOD2 or CDKN2A variants
    Authors: Elżbieta Złowocka-Perłowska, Thierry van de Wetering, Aleksandra Tołoczko-Grabarek, Rodney J. Scott, and Jan Lubiński
  1.  Research Paper: Combined treatment with niclosamide and camptothecin enhances anticancer effect in U87 MG human glioblastoma cells
    Authors: Laura Valdez, Benxu Cheng, Daniela Gonzalez, Reanna Rodriguez, Paola Campano, Andrew Tsin, and Xiaoqian Fang
  1.  Research Paper: Proteomic analysis reveals dual requirement for Grb2 and PLCγ1 interactions for BCR-FGFR1-Driven 8p11 cell proliferation
    Authors: Malalage N. Peiris, April N. Meyer, Dalida Warda, Alexandre Rosa Campos, and Daniel J. Donoghue
  1.  Research Paper: Tazemetostat in relapsed/refractory follicular lymphoma: a propensity score–matched analysis of E7438-G000-101 trial outcomes
    Authors: David G. Proudman, Deepshekhar Gupta, Dave Nellesen, Jay Yang, Beth A. Kamp, Khalid Mamlouk, and Bruce D. Cheson
  1.  Research Paper: Response to immunotherapy in KRAS G12C mutated NSCLC: a single-centre retrospective observational study
    Authors: Carolina Sciortino, Valentina Viglialoro, Massimo Nucci, Mariam Grazia Polito, Enrico Cortesi, Alain Gelibter, Paola Gazzaniga, Chiara Nicolazzo, Marco Siringo, and Salvatore Caponnetto
  1.  Research Paper: CancerOmicsNet: a multi-omics network-based approach to anti-cancer drug profiling
    Authors: Limeng Pu, Manali Singha, Jagannathan Ramanujam, and Michal Brylinski
  1.  Research Paper: NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer
    Authors: Travis P. Schrank, Andrew C. Prince, Tejas Sathe, Xiaowei Wang, Xinyi Liu, Damir T. Alzhanov, Barbara Burtness, Albert S. Baldwin, Wendell G. Yarbrough, and Natalia Issaeva
  1.  Research Paper: Deciphering miR-520c-3p as a probable target for immunometabolism in non-small cell lung cancer using systems biology approach
    Authors: Pooja Gulhane, Prajakta Nimsarkar, Komal Kharat, and Shailza Singh
  1.  Research Paper: HOXB9 mediates resistance to chemotherapy and patient outcomes through the TGFβ pathway in pancreatic cancer
    Authors: Naokazu Chiba, Shigeto Ochiai, Takahiro Gunji, Toshimichi Kobayashi, Toru Sano, Koichi Tomita, and Shigeyuki Kawachi
  1.  Research Paper: Identification of lung cancer drivers by comparison of the observed and the expected numbers of missense and nonsense mutations in individual human genes
    Authors: Olga Y. Gorlova, Marek Kimmel, Spiridon Tsavachidis, Christopher I. Amos, and Ivan P. Gorlov
  1.  Review: Targeting lipid metabolism in the treatment of ovarian cancer
    Authors: Saliha Chaudhry, Stefani N. Thomas, and Glenn E. Simmons Jr.
  1.  Research Paper: IL-33 promotes gastric tumour growth in concert with activation and recruitment of inflammatory myeloid cells
    Authors: Chau P. Tran, Michelle Scurr, Louise O’Connor, Jon N. Buzzelli, Garrett Z. Ng, Sharleen Chung Nien Chin, Lincon A. Stamp, Toshinari Minamoto, Andrew S. Giraud, Louise M. Judd, Philip Sutton, and Trevelyan R. Menheniott
  1.  Research Paper: Are anaplastic lymphoma kinase (ALK) and O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation driver biomarkers of pulmonary neuroendocrine tumors (NETs) and carcinomas (NECs)?
    Authors: Birgitta Hiddinga, Karen Zwaenepoel, Annelies Janssens, Jan Van Meerbeeck, and Patrick Pauwels
  1.  Research Paper: Alectinib after failure to crizotinib in patients with ALK-positive non-small cell lung cancer: results from the Spanish early access program
    Authors: Reyes Bernabé-Caro, Pilar Garrido, Rosario García-Campelo, Ramón Palmero, Ángel Artal, Cristina Bayona, Delvys Rodríguez-Abreu, Marta López-Brea, Alfredo Paredes, David Vicente, José Miguel Sánchez Torres, Margarita Majem, Pilar Diz, Rocío Gordo, Margarita Coca, and Javier de Castro
  1.  Review: Early-onset pancreatic cancer: a review of molecular mechanisms, management, and survival
    Authors: Mark B. Ulanja, Alastair E. Moody, Bryce D. Beutler, Daniel Antwi-Amoabeng, Ganiyu A. Rahman, and Olatunji B. Alese

Visit to read the latest publications in Volume 13.

About Oncotarget: Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science.

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