Author: Kathryn Atkins

Figure 2: Comparison of human LY6 gene expression in normal uterine tissue (n = 146) to expression in uterine corpus endometrial carcinoma (n = 547).

LY6 Gene Family: Potential Tumor Antigens and Prognostic Biomarkers in Endometrial Cancer

May 8, 2023

“Importantly, the expression of several LY6 genes is elevated in UCEC [uterine corpus endometrial carcinoma] when compared to the expression in normal uterine tissue.” Listen to an audio version of… read more

Oncotarget

Systemic AL Amyloidosis: Current Approach and Future Direction

May 5, 2023

“AL amyloidosis is a fatal disease and systemic therapy is required to prevent deposition of amyloid in other organs and prevent progressive organ failure.” Listen to an audio version of… read more

Figure 1: Retinol-mediated suppression of tumor-promoting IL-6 is disrupted in colon cancer-associated fibroblasts.

Oncotarget

Retinol Disruption and the Role of Vitamin A Metabolism in Colon Cancer

May 3, 2023

“Retinoids are known to inhibit tumor-promoting IL-6 production.” Listen to an audio version of this press release BUFFALO, NY- May 3, 2023 – A new research perspective was published in… read more

Oncotarget

Crossroads: The Role of Biomarkers in the Management of Lumps in the Breast

May 2, 2023

“A biomarker or set of biomarkers to inform on the individual progression risk would be beneficial to the patient and cost-effective for the healthcare system.” Listen to an audio version… read more

Figure 3: Cytokine expression and cell viability upon mRNA silencing of STAT3 isoforms

Oncotarget

Differential Silencing of STAT3 Isoforms Leads to Changes in STAT3 Activation

April 26, 2023

“Our study emphasizes the importance of distinguishing between STAT3α and STAT3β proteins and their active forms when discussing STAT3-related cancer diagnosis and therapy.” Listen to an audio version of this… read more

Figure 1: Tumor necroptosis promotes metastasis of breast cancer by suppressing anti-tumor immunity.

Oncotarget

Tumor Necroptosis Promotes Metastasis by Modulating Tumor-Host Immunity

April 25, 2023

“[...] we found that blocking necroptosis leads to the inhibition of metastasis in mouse breast cancer models [...]” Listen to an audio version of this press release BUFFALO, NY- April… read more

Figure 2: Kaplan-Meier survival curve of duodenal adenocarcinoma patients with elevated CA 19-9 (green) and with normal CEA (blue).

Oncotarget

CA 19-9 and CEA in Prognosis of Duodenal Adenocarcinoma: A Retrospective Study

April 18, 2023

“To our knowledge, there are no studies evaluating the prognostic importance of CEA and Ca 19-9 in patients with DA [duodenal adenocarcinoma].” Listen to an audio version of this press… read more