Navigating Bias in AI-Driven Cancer Detection
November 11, 2024
“As we eagerly adopt Al models, we need to take a moment to think about the potential biases that they may contain.” BUFFALO, NY - November 11, 2024 – A… read more
Author: Oncotarget
Precision Medicine in SCLC: DLL3, ASC1, TTF-1, and Ki-67 Expression
November 6, 2024
“This study presents an observational, cross-sectional analysis of 64 patients diagnosed with small cell lung cancer (SCLC) at a reference laboratory for thoracic pathology between 2022 and 2024.” BUFFALO, NY… read more
Immunotherapy Success in KRAS G12C Adenosquamous Pancreatic Cancer
November 4, 2024
“Here, we present a case of metastatic ASCP with a KRAS G12C mutation refractory to multiple lines of systemic therapy, including platinum-based chemotherapy and targeted inhibition of KRAS G12C.” BUFFALO,… read more
Tumor Dormancy Initiated by Lymphovascular Embolus
October 30, 2024
“Both our experimental as well as observational studies indicate that in vivo lymphovascular tumor emboli and their in vitro spheroid equivalent initiate dormancy through these pathways.” BUFFALO, NY- October 30,… read more
Complete Response to Encorafenib + Binimetinib in BRAF V600E-Mutant Tumor
October 29, 2024
“This case report highlights the importance of full tumor genotyping to identify potentially actionable targets in rare tumors such as malignant glomus tumors.” BUFFALO, NY- October 29, 2024 – A… read more
Behind the Study: Molecular Chaperones & Tumor Suppressor Stability
October 24, 2024
Drs. Mehdi Mollapour, Jennifer Heritz, and Sarah Backe from SUNY Upstate Medical University (Syracuse, NY) discuss a review they co-authored that was published by Oncotarget in Volume 15, entitled “Molecular… read more
How Blood Cancer Cells Rewire to Evade Drug Treatment
October 23, 2024
“[...] drugs that target individual signalling pathways in AML often fail to stop proliferation malignant growth, due to the wide variety, redundancy and cross talk between multiple pathways regulating and… read more
Tribute to Dr. Mikhail (Misha) Blagosklonny
October 22, 2024
It is with great sadness and heavy heart that we announce the recent passing of Dr. Mikhail (Misha) V. Blagosklonny, our beloved Editor-in-Chief. Misha succumbed to metastatic lung cancer after… read more
Next-Gen Cell-Penetrating Antibodies for Tumor Targeting and RAD51 Inhibition
October 21, 2024
“Overall, the data presented in this study affirm that humanizing 3E10 preserves its crucial biological properties essential for therapeutic efficacy.” BUFFALO, NY- October 21, 2024 – A new research paper… read more
Molecular Chaperones: Guardians of Tumor Suppressor Stability
October 16, 2024
“Focusing on the holistic lifecycle of these proteins reveals commonalities between the widely diverse group of tumor suppressors, which is invaluable to inform therapy development for multiple cancers.” BUFFALO, NY-… read more