Prostate Cancer Archives | Oncotarget.net

Oncotarget News

Epigenetic Dysregulation of PDX1 Drives Prostate Cancer Progression

April 15, 2026

Aberrant DNA methylation changes lead to abnormal gene expression that contributes to the development and progression of prostate cancer (PCa).”BUFFALO, NY - April 15, 2026 – A new research paper was... read more

Oncotarget

CREB5 Linked to Stem Cell-Like Programs That Promote Prostate Cancer Progression

March 24, 2026

We determined that CREB5 is a key regulator of basal and SCL transcriptional programs and tumor-forming phenotypes in PC.”BUFFALO, NY - March 24, 2026 – A new research paper was published... read more

Oncotarget

Behind the Study: R-spondin Family Roles in Metastatic Prostate Cancer

August 26, 2025

Aiden Deacon from the University of Minnesota-Twin Cities, Minneapolis, discusses a research paper he co-authored that was published in Volume 16 of Oncotarget, titled “Dissecting the functional differences and clinical... read more

Oncotarget

New Gene Linked to Aggressive, Treatment-Resistant Prostate Cancer

August 11, 2025

These findings highlight that, in PC, RSPO2 functions as a unique member of the R-spondin family by promoting genes and signaling pathways associated with aggressive PC, and RSPO2 amplifications are... read more

Oncotarget

Prostate Cancer Cells Survive Treatment by Storing Fat in Low Oxygen Conditions

July 14, 2025

manipulating LD dynamics represents a promising strategy to overcome hypoxia-induced resistance to ferroptosis and improve the success of PCa treatment.”BUFFALO, NY - July 14, 2025 – A new research paper was... read more

Oncotarget

Targeting PCNA-Androgen Receptor Interaction Suppresses Prostate Cancer Cell Growth

June 4, 2025

This finding implicates that targeting PCNA/AR interaction could be an innovative strategy for therapy against CRPC.”BUFFALO, NY - June 4, 2025 – A new research paper was published in Volume... read more